It is not unfeasible to replace antibiotics with probiotics. The key is to find probiotic strains that have the same effect as the antibiotics that need to be replaced. At the same time, scientific and technical support must be provided to provide application solutions to stabilize the effects of probiotics.
Xinmuwang reported on December 29 that the addition of sub-therapeutic doses of antibiotics to livestock and poultry feeds to improve animal performance is positive, and its long-term use as feed is also controversial.
At present, the problem of drug resistance in antibiotics is gradually becoming more prominent, and the application cost is rising. With the public's questioning and questioning about the application of antibiotics, the national regulations are becoming more and more perfect, the management is becoming stricter, and the application of antibiotics is reduced. This is an urgent need of the livestock and poultry feed industry. In this context, the industry is investing more attention in the field of probiotics for the intestinal health of animals.
However, in practical applications, probiotics do not reflect the expected effects on animal intestinal health management. The industry is generally skeptical about the use of probiotics instead of antibiotics. The root cause is mainly concentrated in two aspects:
1, the application effect is mostly not as good as antibiotics
The system of probiotics is very complex. Based on various theories and practices, the characteristics of different strains will vary greatly. Even the same strains and different strains have different characteristics and functions, which are also different. Significant differences in actual application results.
The Ministry of Agriculture approved the catalogue of feed microbes with more than 30 species. There are hundreds of enterprises and hundreds of probiotic products on the market, and the levels are uneven. However, due to the lack of corresponding evaluation methods and means to verify Effect, in practical applications, probiotics are used as a "placebo".
2, the use of probiotics is unstable
On the one hand, the stability of the probiotic is determined by the characteristics of the strain itself, whether it is applied in the feed, whether it has good resistance to stress, and resists the effects of high-temperature granulation; whether it can withstand acid in the body during feeding And the physiological environment of bile salts; compared with antibiotics, the significant differences in the stability of these strains, in the absence of assessment, easy to wrong choice, resulting in unsatisfactory results.
Second, the health management of the intestines is often a comprehensive drug compatibility program. No probiotics can be compatible with all drug dosages. In practice, due to the lack of systematic compatibility testing, blind use of probiotics is likely to result in The incompatibility of other drug combinations in the feed is reflected in the specific effects and will therefore be greatly reduced.
Then, can the probiotics program effectively reduce the dependence on antibiotics? The key to solving this problem is to select the correct probiotics program through systematic evaluation, clear two aspects:
1, good probiotics must have a clear effect
Can effectively reduce the application of antibiotics, can be reflected in the use effect can not be comparable to antibiotics; the effect of antibiotics often depends on its inhibition of a certain class of harmful bacteria, so effective probiotics only have antibacterial effect close to antibiotics, It is possible to replace or partially replace antibiotics. Through professional laboratory support and in vitro antibacterial comparison test, it can clearly and intuitively compare the inhibition of pathogenic harmful bacteria between probiotics and antibiotics and between different probiotics. Killing ability; thus intuitively assessing the actual application effect.
Through systematic assessment on the effect of the application, select probiotic products comparable to antibiotics, which are effective in reducing antibiotic dependency, scientific selection of probiotics tool first step
2, customized and reasonable application program, in order to make probiotics have a stable performance
High-temperature granulation in feed production, environmental impacts of long-term storage, physicochemical conditions of acid and bile salts in livestock and poultry, etc. These factors affect the application stability of probiotics; detection of probiotics in feed after high-temperature granulation Test methods such as the rate, the acidity of the body and the survival rate of probiotics in the simulated environment of bile salts, systematically compare the stability of different probiotics, and select strains with excellent stress resistance, which is the basic factor for ensuring the stable use of probiotics.
In actual production, intestinal health requires systematic and comprehensive management measures, often requiring both antibiotics, coccidiosis, and acidifier addition programs. Before using probiotics, it is necessary to know whether the probiotics can be compatible with antibiotics or other products. This requires comprehensive testing of the compatibility of probiotics, through the professional probiotic compatibility test program, to understand the compatibility of probiotics with antibiotics, coccidiostats and acidifiers, and rational allocation of probiotics based on antimicrobial properties and compatibility. And the dose of antibiotics, tailored, tailored to a reasonable application.
In summary, the replacement of antibiotics by probiotics is not unfeasible. The key is to find probiotic strains that have the same effect as the antibiotics that need to be replaced. At the same time, there must be scientific and systematic technical support to provide application solutions to make probiotics effective. Get a steady play. Professional laboratory project support and customized system evaluation are undoubtedly the key elements for the rational selection of probiotics and application solutions.
Proper selection of probiotics, reducing the use of antibiotics, although urgent but not blind. Scientific assessment and selection of probiotics can help you in the industry reshuffle.
It is understood that probiotics are complex biological preparations refined by fermentation, purification and drying of animal enteric beneficial microorganisms approved by the Ministry of Agriculture. They are ideal green additives for reducing or replacing antibiotics.
Tips: Prebiotics use precautions
1. Broilers should be fed probiotics starting from 3 days of age, and pigs should be fed from half a month later.
2. Relationship with antibiotic additives: Take broiler chickens as an example. One week after feeding probiotics at 3 days of age, use antibiotics to prevent diseases at most once, or chickens must be treated with antibiotics, and probiotics should be stopped with antibiotics.
3. When probiotics are added to drinking water, disinfect the animal's drinking water one or two days in advance, and reduce the amount of disinfectant or add probiotics before drinking.
4. Avoid using it with feeds with antibiotics, otherwise it will affect the use of probiotics.
5. This product should be used up as soon as possible after opening the package to avoid product failure. Quick-solving enzymes - make probiotics double the effect. Function: In the intestinal catalysis process, oxygen is consumed in the intestinal tract, creating an anaerobic environment and laying a good foundation for colonization of probiotics. According to the network information report
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